Pressure gradient measurement in the coronary artery using 4D PC-MRI: towards noninvasive quantification of fractional flow reserve
نویسندگان
چکیده
Background Fractional flow reserve (FFR) is an invasive procedure evaluating the functional significance of an intermediate stenosis by measurement of pressure drop across stenosis [1]. Noninvasive pressure measurement technique i.e. Phase-contrast (PC)-MRI has been studied in the cardiac chamber[2], aorta[3], and renal[4] arteries. The purpose of this study was to investigate the feasibility of pressure gradient quantification using 4DPC-MRI in the coronary arteries, which may allow for the derivation of FFR associated with stenosis.
منابع مشابه
Reproducibility of phase-contrast MRI in the coronary artery: towards noninvasive pressure gradient measurement and quantification of fractional flow reserve
Background Fractional Flow Reserve (FFR) is an invasively determined index of the functional severity of an intermediate coronary stenosis by measuring the pressure drop across the lesion [1]. Noninvasive pressure gradient (ΔP) measurements using phase-contrast (PC)-MRI have been attempted in the aorta, carotid, and renal arteries [2-4]. The purpose of this study is to assess the reproducibilit...
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Background Fractional flow reserve (FFR) is an invasive diagnostic tool to evaluate the functional significance of an intermediate coronary stenosis by quantifying the pressure gradient (ΔP) across that stenosis [1]. Noninvasive ΔP measurement (ΔPMR) using phase-contrast (PC)-MRI in conjunction with Navier-Stokes (NS) equations has been attempted in large to medium size vessels [2-4], and recen...
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Background Fractional flow reserve (FFR) is an invasive procedure evaluating the functional significance of an intermediate coronary stenosis in patients with coronary artery disease (CAD) [1]. Quantification of pressure gradient (ΔP) across a particular stenosis is the key to the determination of FFR. Noninvasive ΔP measurement (ΔPMR) using phase-contrast (PC)-MRI in conjunction with NavierSto...
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